【摘 要】
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Stem cell aging is one of the leading theories of aging and is gaining momentum in recent years with the development of new technologies to study stem cells (Sc
【机 构】
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Huffington Center on Aging, Baylor College of Medicine, Houston, TX 77030, USA
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Stem cell aging is one of the leading theories of aging and is gaining momentum in recent years with the development of new technologies to study stem cells (Schultz & Sinclair,2016).In the stem cell aging theory, the age-associated physiological changes and functional declines at tissue and organismal levels are attributed to changes to various stem cell populations, both in their quantity and function.Hence,one of the pressing questions in the aging research is to understand the molecular mechanisms that preserve stem cell function and delay their aging process.In this issue, Bi,et al., reports a novel mechanism that slows down the aging process in human mesenchymal stem cells by preserving the structure of heterochromatin, which is mediated through the functions of SIRT7, one of the seven sirtuins found in all mammals (Bi et al., 2020).
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