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作者对18名冠心病患者用放射性核素方法(闪烁探子和放射性铟)测定左室射血分数,舒张末期容量和心输出量,以及对投给心得安(口服20毫克,40毫克或80毫克后两小时)硝酸甘油(0.4舌下)和这两种药联合投给的作用进行了测定。测定结果:投给硝酸甘油减少了左室舒张末期容量,每搏输出量和收缩期动脉血压,增加了左室射血分数和心率,其心脏指数在正常范围内。口服20毫克心得安后所检查的12个人,左室舒张末期容量,每搏输出量和左室射血分数的平均值同对照
The authors measured left ventricular ejection fraction, end-diastolic volume, and cardiac output using a radionuclide assay (scintillation detector and radioactive indium) in 18 patients with coronary heart disease and propranolol (20 mg, 40 mg, or 80 mg orally administered Two hours after) nitroglycerin (0.4 sublingual) and the combination of these two drugs were measured. Results: Nitroglycerin administration reduced left ventricular end-diastolic volume, stroke volume and systolic arterial pressure, increased left ventricular ejection fraction and heart rate, and had a cardiac index within the normal range. After oral administration of 20 mg of propofol, 12 individuals examined, the left ventricular end diastolic volume, stroke volume and left ventricular ejection fraction average with the control