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目的:研究缬沙坦、氨氯地平联合用药方案对社区老年高血压伴2型糖尿病患者血压和血糖控制的影响。方法:选择从2012年3月至2014年11月于我院接受治疗的112例社区老年高血压伴2型糖尿病患者作为研究病例,分为研究组和对照组两组,对照组患者给予单纯缬沙坦进行治疗,研究组患者给予缬沙坦、氨氯地平联合用药进行治疗。比较用药后两组患者血压和血糖的情况。结果:用药后,研究组患者的SBP下降幅度、DBP下降幅度、餐前血糖、餐后2h血糖指标均显著优于对照组,差异均具有统计学意义(P<0.05)。结论:缬沙坦、氨氯地平联合用药方案可以显著地控制社区老年高血压伴2型糖尿病患者血压和血糖,适合临床推广应用。
Objective: To study the effects of combination regimen of valsartan and amlodipine on blood pressure and blood sugar control in elderly hypertensive patients with type 2 diabetes mellitus. Methods: From March 2012 to November 2014 in our hospital for treatment of 112 elderly patients with hypertension and type 2 diabetes mellitus as a case study, divided into two groups of study group and control group, the control group patients given simple Valerian Sartan for treatment, study group patients given valsartan, amlodipine combined treatment for treatment. Compare the two groups of patients after treatment of blood pressure and blood glucose. Results: After treatment, the decrease of SBP, the decrease of DBP, the pre-meal blood glucose and the postprandial 2-hour postprandial blood glucose of the study group were all significantly better than those of the control group. The difference was statistically significant (P <0.05). Conclusion: Combination of valsartan and amlodipine can significantly control the blood pressure and blood glucose of elderly patients with type 2 diabetes mellitus in community. It is suitable for clinical application.