“乙酰胆碱的放射免疫测定”一文发表以后,不少读者来信来访,询问本法能否用于血液中乙酰胆碱(ACh)的测定。在红细胞膜表面,存在着真性胆碱酯酶(ACHE),血浆中存在着假性胆碱酯酶(ChE)。由于水解酶类的强烈作用,一般讲来血液中ACh浓度是很低的。但在中毒及某些病理状态下,血液中是否存在ACh,是一个值得回答的问题。 After the publication of “Radioimmunoassay for Acetylcholine,” many readers wrote a letter asking if this law could be used for the determination of acetylcholine (ACh) in the blood. Erythrocyte membrane surface, there is a true cholinesterase (ACHE), the presence of pseudo-cholinesterase in plasma (ChE). Due to the strong role of hydrolases, ACh concentrations in blood are generally low. But in the poisoning and some pathological conditions, the presence or absence of ACh in the blood, is a question worthy of answer.