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目的:探讨曲霉菌感染的临床特点及诊断治疗。方法:对21例曲霉菌感染病例的临床资料进行回顾性分析。结果:21例曲霉菌感染者皆有基础疾病,两种或两种以上基础疾病者19例(90.5%),气管切开等创伤性治疗16例,使用免疫抑制17例。采取科玛嘉显色培养和沙氏培养结合多次真菌镜检,可缩短诊断时间。伊曲康唑对曲霉感染疗效较好。结论:对创伤性治疗和长期使用免疫抑制剂及多种抗生素住院患者,应警惕曲霉菌感染。一旦诊断成立,应尽早治疗。
Objective: To investigate the clinical characteristics and diagnosis and treatment of Aspergillus infection. Methods: The clinical data of 21 cases of Aspergillus infection were retrospectively analyzed. RESULTS: Twenty-one patients with aspergillosis had underlying diseases, 19 (90.5%) with two or more underlying diseases, 16 with traumatic tracheotomy and 17 with immunosuppression. Take Kema Jia color culture and sand culture combined with multiple fungal microscopy, can shorten the diagnosis time. Itraconazole good effect on Aspergillus infection. CONCLUSIONS: Aspergillus infection should be wary of traumatic treatment and long-term use of immunosuppressive agents and multiple antibiotic inpatients. Once diagnosed, should be treated as soon as possible.