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目的:对比氟比洛芬酯应用于重症肌无力术后的镇痛效果。方法:选取扩大范围胸腺切除术的成年患者35例,观察组术后予氟比洛芬酯缓慢静脉滴注,对照组予曲马多肌肉注射,记录用药前后的VA S评分、SpO2变化及不良反应出现情况。结果:观察组疼痛缓解率98%,对照组42%;出现不良反应观察组4例,对照组6例,对症处理后症状缓解,两组患者皆无肌无力危象发生。结论:氟比洛芬酯用于重症肌无力患者术后镇痛安全有效,不良反应发生率低,不诱发肌无力危象。
Objective: To compare the analgesic effects of flurbiprofen in patients with myasthenia gravis. Methods: Thirty-five adult patients with extended thymectomy were enrolled. The patients in the observation group received slow intravenous infusion of flurbiprofen axetil and the control group received intramuscular injection of tramadol. VA S scores, SpO2 changes and malformations were recorded before and after treatment Reaction occurred. Results: The pain relief rate was 98% in the observation group and 42% in the control group. There were 4 patients in the adverse reaction observation group and 6 patients in the control group. The symptoms were relieved after symptomatic treatment, and no muscle weakness crisis occurred in both groups. CONCLUSION: Flurbiprofen axetil is safe and effective for the postoperative analgesia in patients with myasthenia gravis. The incidence of adverse reactions is low, and the myasthenic crisis is not induced.