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本文用自行设计组装的Ｍ１ＰＳ－Ｉ型自动图像分析仪对２１例直肠癌组织切片进行细胞核ＤＮＡ多数测定，并探讨其５项指标与患者预后的关系，结果发现：生存期≥５年和＜５年两组的（１）ＤＮＡ指数均值（２）分布宽度（ａ）ＤＮＡ主干系水平［（倍体，Ｃ）］间有显著性差异（ｐ＜０．０５）。（４）两组患者的ＤＮＡ类型有２／３是异借体，１／３是多倍体，仅１例为二俗体，本文６Ｃ峰位细胞是直肠癌５年生存期的分界值，＜６Ｃ者，预后好，≥６０者，顶后差。（５）按患者细胞群体ＤＮＡ分布中主干系峰位的ＤＩ（Ｃ）值，分为三种峰型，Ⅰ型峰预后好，Ⅱ型峰次之，Ⅲ型峰最差。图像细胞定量化学表明，此为直肠癌独立的预后变量，这对Ｄｕｋｅｓ系统是一个极有价值的补充。
In this paper, the majority of 21 cases of rectal cancer tissue sections were determined for nuclear DNA by self-designed and assembled M1PS-I automatic image analyzer. The relationship between the five indicators and the prognosis of patients was explored. The results showed that the survival period was ≥5 years and <5. There were significant differences between the two groups in the (1) DNA index mean (2) distribution width (a) DNA backbone level [(ploid, C)] (p<0.05). (4) Two-thirds of the DNA types in the two groups are allogeneic, 1/3 is polyploid, and only 1 is a second-class body. The 6C peak cell in this study is the cut-off value of 5-year survival for rectal cancer. <6C, the prognosis is good, ≥ 60, poor after the top. (5) According to the DI (C) value of the main system peak in the DNA distribution of the patient’s cell population, it is divided into three peak types. The I-type peak has a good prognosis, the II-type peak is the second, and the III-type peak is the worst. Image cell quantification chemistry shows that this is an independent prognostic variable for rectal cancer, which is an extremely valuable supplement to the Dukes system.