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目的:观察苦参素联合胸腺五肽抗乙型肝炎病毒的疗效。方法:将慢性乙型肝炎100例随机分为观察组和对照组各50例。对照组采用护肝、降酶及一般对症治疗;观察组在对照组治疗基础上,加用苦参素和胸腺五肽治疗,比较两组治疗有效率,两组治疗前后丙氨酸转氨酶(ALT)和总胆红素(TBil)水平变化。结果:观察组有效16例,有效率32.0%;对照组有效6例,有效率12.0%,两组比较,差异显著(P<0.05)。两组治疗前后ALT、TBil水平比较,差异显著(P<0.05);治疗后两组ALT、TBil水平比较,同样差异显著(P<0.05)。结论:苦参素联合胸腺五肽治疗慢性乙型肝炎有一定疗效。
Objective: To observe the curative effect of oxymatrine and thymopentin against hepatitis B virus. Methods: 100 cases of chronic hepatitis B were randomly divided into observation group and control group, 50 cases each. The control group was treated with liver protection, enzyme-lowering therapy and general symptomatic treatment. The observation group was treated with kushenin and thymopentin on the basis of the control group, and the treatment efficiency was compared between the two groups. Before and after treatment, alanine aminotransferase (ALT ) And total bilirubin (TBil) levels. Results: The observation group was effective in 16 cases, the effective rate was 32.0%. In the control group, 6 cases were effective and the effective rate was 12.0%. There was significant difference between the two groups (P <0.05). The levels of ALT and TBil in the two groups before and after treatment were significantly different (P <0.05). After treatment, the levels of ALT and TBil in the two groups were also significantly different (P <0.05). Conclusion: Oxymatrine combined with thymopentin in the treatment of chronic hepatitis B has a certain effect.