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目的：本文联合应用纳诺酮、尿激酶及低分子肝素治疗３５例急性脑梗塞（ＡＣＩ）患者（治疗组），观察其治疗前后的β－内啡肽（β－ＥＰ）改变及临床疗效，方法：并与３０例常规药物治疗组（对照组）比较。结果：结果显示，两组患者的血浆β－ＥＰ浓度均明显高于正常组，治疗组治疗后，其β－ＥＰ浓度显著下降，临床疗效明显高于对照组。提示纳络酮能明显降低（ＡＣＩ）患者的血浆β－ＥＰ浓度。结论三药联合应用的临床疗效明显优于对照组。
Objective: In this study, 35 patients with acute cerebral infarction (ACI) were treated with naltrexone, urokinase and low molecular weight heparin (ACI). The changes of β-EP and its clinical efficacy before and after treatment were observed. Methods: And compared with 30 cases of conventional drug treatment group (control group). Results: The results showed that plasma β-EP levels in both groups were significantly higher than those in the normal group. After treatment, the concentration of β-EP was significantly decreased, and the clinical efficacy was significantly higher than that of the control group. Tip Naloxone can significantly reduce (ACI) in patients with plasma β-EP concentration. Conclusion The clinical efficacy of the combination of three drugs was significantly better than the control group.