前列腺肿瘤干细胞是否存在?这是一个比较棘手的题目,包括本人在内的研究者遇到这一问题可能都会带有一定的主观色彩,对于免疫染色、克隆球形成实验或者移植瘤模型这些方法是否能作为检测干细胞的金标准,仍有待商榷。另外,到底能否把表达干细胞标记物,具有克隆球形成能力并且/或者能够 Prostate cancer stem cells exist? This is a tricky topic, researchers including myself encountered this problem may be with a certain subjective, for immunostaining, cloning sphere formation experiments or xenograft model these methods are Can be used as the gold standard for detecting stem cells, remains to be discussed. In addition, whether stem cell markers can be expressed, clonal sphere-forming ability and /