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环糊精(CDs)是芽饱杆菌产生的环糊精葡萄糖基转移酶作用直链淀粉的产物,即一系列环状低聚糖的总称,其结构外亲水、内疏水的性能致使其在医药、食品、环境保护、农业、轻工和化工等多方面的应用范围越来越广泛。介绍β-环糊精(β-CD)的化学修饰方法、酶工程修饰方法以及β-环糊精聚合物,修饰后的环糊精衍生物具有某些特定功能,如较好的水溶性或环境刺激响应性等,它们在药物控制释放领域有着新颖而广泛的应用。
Cyclodextrins (CDs) are the products of amylose produced by buds of B.subtilis. They are the general name of a series of cyclic oligosaccharides. Its structure is hydrophilic and its internal hydrophobic properties make it Medical, food, environmental protection, agriculture, light industry and chemical industry and other aspects of the application of more and more extensive. The chemical modification method, enzyme engineering modification method and β-cyclodextrin polymer of β-cyclodextrin (β-CD) are introduced. The modified cyclodextrin derivatives have certain specific functions such as better water solubility or Environmental stimuli responsiveness, etc., which have new and broad applications in the field of drug controlled release.