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目的观察负压吸引术终止妊娠术前用米索前列醇不同给药途径对宫颈产生的扩张效果。方法选择2010-2011年在我院妇科门诊自愿选用负压吸引术终止妊娠者300例,分为对照组(不给药)100例和给药组200例,给药组分口服和阴道后穹窿给药各100例。给药组术前口服或阴道后穹窿放置米索前列醇0.4mg,同时观察各组宫颈扩张程度及给药后产生的不良反应。结果给药组的宫颈扩张有效率62.0%以上,对照组41.0%;给药组间宫颈扩张程度无统计学意义;用药后不良反应发生率,口服组高于阴道后穹窿组。结论负压吸引术前应用米索前列醇口服或阴道后穹窿给药,均能扩张宫颈,且疗效相似,阴道后穹窿给药优于口服,它可减少口服给药带来的不良反应,且操作简便、有效安全,建议在基层推广应用。
Objective To observe the effects of misoprostol on cervical dilation before the termination of negative pregnancy with negative pressure aspiration. Methods 300 cases of voluntary termination of pregnancy by gynecology outpatient clinic in our hospital from 2010 to 2011 were divided into control group (100 cases) and control group (200 cases). The components of oral administration and vaginal fornix Each of the 100 administrations. Oral administration group before or oral vaginal fornix placed 0.4 mg misoprostol, while observing the extent of cervical dilatation and adverse reactions after administration. Results The effective rate of cervical dilatation in the treatment group was over 62.0% and in the control group 41.0%. There was no significant difference in the cervical dilation between the two groups. The incidence of adverse reactions in the oral administration group was higher than that in the vaginal fornix group. Conclusions Oral or vaginal fornix administration before misoprostolysis can both expand the cervix and have similar curative effect. Administration of vaginal posterior fornix is superior to oral administration, which can reduce adverse reactions caused by oral administration and Easy to operate, effective and safe, it is recommended to promote the use of grassroots.