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唾液腺淋巴上皮癌是原发于唾液腺的一种较为罕见的恶性肿瘤,最早于1962年由Hilderman首次报道并提出,曾有多个别名,如淋巴上皮瘤样癌、恶性淋巴上皮病变、伴淋巴样间质的未分化癌以及癌在淋巴上皮病变中。WHO头颈肿瘤分类第3版(2005年)正式将其更名为淋巴上皮癌。唾液腺淋巴上皮癌的临床诊治尚未规范。本文旨在针对唾液腺淋巴上皮癌的发病机制、临床病理特点、诊断、治疗和预后进行综述。
Salivary gland lymphoepithelial carcinoma is a relatively rare malignant tumor originating in the salivary gland. It was first reported and suggested by Hilderman in 1962 that there were multiple aliases such as lymphoepithelioma-like carcinoma, malignant lymphoepithelial lesion, Interstitial undifferentiated carcinoma and carcinoma in lymphoepithelial lesions. WHO classification of head and neck cancer 3rd edition (2005) officially changed its name to lymphoid epithelial cancer. Clinical diagnosis and treatment of salivary gland lymphoepithelial carcinoma has not been standardized yet. This article aims to review the pathogenesis, clinicopathological features, diagnosis, treatment and prognosis of salivary gland lymphoepithelial carcinoma.