论文部分内容阅读
作者用动力顶空气质联机法测定了431名工作中不接触苯者的血苯。431名均为健康成人,根据居住和工作地点分为农村组和城市组各155名和276名,平均年龄39.2岁(SD=11.3岁);其中293名为不吸烟者,138名为吸烟者。用玻璃管注射器抽取血样5～10 ml,将血样放于有2滴10％的乙二胺四醋酸溶液的玻璃管中,并且要灌满以免血液表面与管盖之间残存气泡,管盖衬以聚四氟乙烯橡胶密封圈。摇动后将血样于4℃保存。测定结果,平均血苯浓度为262 ng/L,农村的(200 ng/L)明显低于城市的(296 ng/L);293名不吸烟者与138名吸烟者的分别为205ng/L 和381 ng/L。在不吸烟者中,76名化工工人的血苯浓度明显较高(307ng/L)。无论农村组还是城市组,不吸烟者与吸烟者血苯浓度都有明显差异。在431名研究对象中,95％的不吸烟者与吸烟者血苯低于514 ng/L 与900ng/L。据此将一般人群的血苯参考值定为901
The authors used kinetic headspace-based on-line method to determine the blood benzene of 431 workers who were not exposed to benzene at work. 431 were healthy adults and divided into 155 and 276 rural and urban groups based on place of residence and place of work, with an average age of 39.2 years (SD = 11.3 years); 293 were non-smokers and 138 smokers. Blood samples were drawn using a glass tube syringe 5 to 10 ml, the blood sample was placed in a glass tube with 2 drops of 10% ethylenediaminetetraacetic acid solution and filled to avoid residual air bubbles between the blood surface and the tube cover, tube cover PTFE rubber seals. Blood samples were stored at 4 ° C after shaking. The results showed that the mean blood benzene concentration was 262 ng / L and that of rural (200 ng / L) was significantly lower than that of the urban (296 ng / L); 205 ng / L for 293 non-smokers and 138 smokers 381 ng / L. Among non-smokers, blood levels of 76 chemical workers were significantly higher (307 ng / L). There was a significant difference in blood benzene concentrations between non-smokers and smokers in both rural and urban settings. Among 431 subjects, 95% of non-smokers and smokers had less than 514 ng / L and 900 ng / L blood benzene. Accordingly, the general population’s blood benzene reference value of 901