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目的探讨胃癌高发区人群慢性胃炎发病和社会心理因素的相关性。方法 以经过确诊的93例慢性浅表性胃炎(CSG)和69例萎缩性胃炎(CAG)患者作为研究对象,健康志愿者作对照组,了解上述人群各项社会心理因素情况。结果 (1)CSG组人际关系敏感、强迫症所占比例明显高于对照组(P均<0.005),睡眠差高于对照组(P<0.05)。(2)女性CSG患者焦虑、抑郁所占比例明显高于男性CSG患者(P均<0.005),负性应激事件及人际关系敏感高于男性CSG患者(P均<0.05)。(3)CAG组强迫症明显高于对照组(P<0.005),人际关系敏感高于对照组(P<0.05)。(4)女性CAG患者抑郁所占比例明显高于男性CAG患者(P<0.005),焦虑所占比例高于男性CAG患者(P<0.05)。结论 (1)该区人际关系敏感、强迫症状与CSG发病密切相关,睡眠差与CSG发病相关。(2)CAG发病与人际关系敏感相关,与强迫症密切相关。(3)女性人群应注意调整自我心理状态,以降低慢性胃炎发病率或减轻其症状。
Objective To investigate the correlation between chronic gastritis and psychosocial factors in high incidence area of gastric cancer. Methods Ninety-three patients with chronic superficial gastritis (CSG) and 69 patients with atrophic gastritis (CAG) were enrolled in this study. Healthy volunteers were used as control group to understand the various social and psychological factors in these groups. Results (1) The interpersonal sensitivity and obsessive compulsive disorder in CSG group were significantly higher than those in control group (all P <0.005). The sleep difference was higher in CSG group than in control group (P <0.05). (2) The proportion of anxiety and depression in female CSG patients was significantly higher than that of male CSG patients (all P <0.005), negative stress events and interpersonal relationship were higher than male CSG patients (all P <0.05). (3) OCD in CAG group was significantly higher than that in control group (P <0.005), and the interpersonal sensitivity was higher than that in control group (P <0.05). (4) The proportion of female CAG patients with depression was significantly higher than that of male CAG patients (P <0.005), and the proportion of anxiety was higher than male CAG patients (P <0.05). Conclusion (1) The interpersonal sensitivity in the district, obsessive-compulsive symptoms and the incidence of CSG are closely related to poor sleep and CSG incidence. (2) The incidence of CAG is sensitive to interpersonal relationship and closely related to OCD. (3) The female population should pay attention to adjust self-psychological state to reduce the incidence of chronic gastritis or reduce their symptoms.