顺氯铵铂(Cis—DiamminedichloroplatihumⅡ,简称CDDP,DDP,PDD,CACP),亦称顺铂(Cis—platintinum或Cisplantin,platinol),是一种重金属无机盐类抗癌药。其分子式为N_2Cl_2PtH_6;分子量300;在1mg/ml浓度时溶于水。早在1965年,Rosenberg等就发现铂复合物对大肠杆菌的增殖有抑制作用。以后,在动物实验中进一步证实:CDDP具有较明显的广谱的抗癌作用。1972年开始,CDDP Cis-Diamminedichloroplatihum II (abbreviated as CDDP, DDP, PDD, CACP), also known as Cis-platintinum or Cisplantin (platinol), is a heavy metal inorganic salt anticancer drug. Its molecular formula is N 2 Cl 2 PtH 6; molecular weight 300; dissolved in water at a concentration of 1 mg/ml. As early as 1965, Rosenberg et al. found that platinum complexes inhibited the proliferation of E. coli. Later, in animal experiments, it was further confirmed that CDDP has a broad spectrum of anti-cancer effects. Since 1972, CDDP