目的分析门急诊抗菌药物使用合理性,提高抗菌药物的疗效,降低不良反应,减少其耐药性。方法随机抽取我院2011年1～9月份处方3720张,抗菌药物处方952张,点评抗菌药物使用合理性。结果门急诊使用抗菌药物不合理处方342张,占抗菌药物总处方的25.6%。不合理问题主要有:无指征用药、选择抗菌药物不适宜、使用频次不合理、用法用量不适宜(单剂量不足或超量)、联合用药不合理、越级使用抗菌药物等。结论通过处方专项点评,并实施适宜的干预,使抗菌药使用更趋合理性。 Objective To analyze the rational use of antimicrobial agents in outpatient and emergency department, improve the curative effect of antimicrobial agents, reduce adverse reactions and reduce their drug resistance. Methods A total of 3720 prescriptions were collected from January to September in 2011 in our hospital. 952 prescriptions of antibiotics were given. The rationality of antibacterials usage was reviewed. Results The outpatient and emergency department used 342 unreasonable prescriptions of antibiotics, accounting for 25.6% of the total prescriptions of antibiotics. Unreasonable problems are: no indications for medication, choice of antimicrobials inappropriate, the frequency of use is not reasonable, the amount used inappropriate (single dose less than or excessive), combined medication unreasonable, leapfrog use of antimicrobial agents. Conclusion Through the prescription of special comments, and the implementation of appropriate intervention, the use of antibacterial drugs more rational.