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目的总结肺曲菌球病的临床特点。方法回顾性分析21例肺曲菌球病患者的临床资料。结果肺曲菌球病症状多表现为反复咳嗽、咳痰、咯血等;影像学主要表现为球状影合并空洞9例,团块或结节影12例;确诊方法:经外科手术病理确诊18例,经纤维支气管镜镜下支气管黏膜活检确诊3例;21例肺曲菌球病中9例误诊,误诊率达42.9%,误诊为肺结核、肺癌、支气管扩张。结论肺曲菌球病临床表现无特异性,多有原发病,容易造成误诊。确诊主要依赖于病理学检查。目前手术仍是肺曲菌球病的主要治疗方法,抗真菌药治疗效果欠佳。
Objective To summarize the clinical features of pulmonary aspergillosis. Methods The clinical data of 21 patients with pulmonary aspergillosis were retrospectively analyzed. Results The symptoms of pulmonary aspergillosis mostly manifested as repeated cough, expectoration and hemoptysis. The main manifestations of the imaging were as follows: 9 cases with globular shadow and 12 cases with clumps or nodules; Diagnosis method: 18 cases were confirmed by surgical pathology , 3 cases were diagnosed by bronchoscopy under bronchoscopy; 9 cases were diagnosed as misdiagnosis (42.9%) in 21 cases of pulmonary aspergillosis and misdiagnosed as pulmonary tuberculosis, lung cancer and bronchiectasis. Conclusion Pulmonary aspergillosis clinical manifestations of non-specific, more than the original disease, easily lead to misdiagnosis. The diagnosis depends mainly on pathological examination. Surgery is still the main treatment of pulmonary aspergillosis, antifungal treatment ineffective.