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观察320例妊娠1～3个月子宫内膜螺旋动脉的变化,材料来自刮宫标本,其中75例为初产妇,245例为经产妇。在这些材料中发现了部分类似晚妊期妊毒症妇女胎盘螺旋血管急性粥样变的病灶。初产妇与经产妇相比,血管病变率比后者要高,其差异具有统计学意义。光镜下,主要病变表现为血管内膜增生伴泡沫细胞形成。AB—PAS染色可于血管内膜中见酸性粘多糖类物。本文就以上发现讨论了早妊期螺旋动脉病变与妊毒症的关系。
Observed 320 cases of endometrial spiral arterial changes in 1 to 3 months of pregnancy, materials from the curettage specimens, of which 75 cases were primary and 245 cases of maternal. Some of these materials were found to resemble acute placental spiral venous atherosclerotic lesions in women with preeclampsia. Compared with the latter, the incidence of vascular lesions was higher in the first trimester than in the latter, and the difference was statistically significant. Under light microscopy, the main lesions showed intimal hyperplasia with foam cell formation. AB-PAS staining can see acid mucopolysaccharides in the vascular intima. This article discusses the relationship between early pregnancy spiral arterial disease and pregnancy.