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本文以微量中和试验法对≤39岁健康人群血清标本257份进行抗体水平调查。结果表明:本地区健康人群脊灰Ⅰ、Ⅱ、Ⅲ型中和抗体阳性率分别为84.60％、82.66％、70.08％。抗体几何平均滴度(GMT)分别为28.08、49.04、9.50,三型抗体全阳性率为59.56％,全阴性率5.23％,抗体GMTⅠ型和Ⅲ型明显低于Ⅱ型,不同年龄组间有显著差异(P<0.01),以2～4岁组最高。但4岁后出现大幅度下降,实为值得注意的问题,应采取相应措施,重视和加强4岁复种工作,并大力开展6岁,13岁普种工作。
In this paper, micro-neutralization test method for serum antibody levels of 257 serum samples of ≤39 years of age were investigated. The results showed that the positive rates of type I, type II and type III neutralizing antibodies in healthy population were 84.60%, 82.66% and 70.08% respectively. The average geometric mean antibody titers (GMTs) were 28.08, 49.04 and 9.50 respectively. The positive rates of the three types of antibodies were 59.56% and 5.23%, respectively. The GMT Ⅰ and Ⅲ antibodies were significantly lower than those of type Ⅱ, with significant differences between different age groups (P <0.01), the highest in group 2 to 4 years old. However, a substantial drop after 4 years of age is a problem worth noting. Measures should be taken to attach importance to and strengthen the 4-year-old multi-cropping work and vigorously carry out all-around work of 6-year-olds and 13-year-olds.