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单克隆抗体(McAb)对于恶性肿瘤的诊断具有特异性强、敏感性高的特点。我科应用第四军医大学西京医院消化病研究室惠赠的胃癌McAbMG_9,对各种组织学类型胃癌和伴有肠化和/或不典型增生的胃炎进行免疫组化染色检查,以探讨胃癌相应抗原在胃癌和胃炎中的表达特征。并检测淋巴结中胃癌转移率,试图评价免疫组化法对提高淋巴结转移检出率的价值。材料与方法一、标本:胃炎65例。胃癌68例,其中29例淋巴结均未见癌细胞者称为阴性组;29例淋巴结部分有转移者称为阳性组。不含所有淋巴结均有癌转移的病例。58例共计205枚
Monoclonal antibodies (McAbs) are highly specific and sensitive to the diagnosis of malignant tumors. Our department applied the gastric cancer McAbMG_9 from the Xijing Hospital Digestive Disease Research Laboratory of the Fourth Military Medical University to perform immunohistochemical staining on various histological types of gastric cancer and gastritis with intestinal metaplasia and/or dysplasia to investigate the corresponding antigens of gastric cancer. Expression characteristics in gastric cancer and gastritis. And to detect the metastasis rate of gastric cancer in lymph nodes, trying to evaluate the value of immunohistochemistry to improve the detection rate of lymph node metastasis. Materials and Methods 1. Specimens: 65 cases of gastritis. Of the 68 cases of gastric cancer, 29 of them had no lymph nodes and no cancer cells were referred to as the negative group; 29 of the lymph nodes had metastases known as the positive group. Does not include all cases of lymph node metastasis. 58 cases totaling 205