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采用间接免疫荧光法对50例急性下呼吸道感染患儿和50例健康儿童进行外周血T淋巴细胞亚群检测,结果显示急性下呼吸道感染时CD_3、CD_4、CD_4/CD_8均明显下降(P0.05)。提示急性下呼吸道感染时可引起T淋巴细胞亚群紊乱,导致免疫功能降低。
Fifty children with acute lower respiratory tract infection and 50 healthy children were tested for T lymphocyte subsets by indirect immunofluorescence. The results showed that CD_3, CD_4 and CD_4 / CD_8 were significantly decreased in acute lower respiratory tract infection (P <0 .O1), the decline of severe children was more significant, while there was no significant change of CD_8 (P> 0.05). Prompt acute lower respiratory tract infection can cause T lymphocyte subsets disorder, resulting in reduced immune function.