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不破裂卵泡黄素化综合征(LUFS)多发生于月经失调妇女,并为女性不孕特别是难解释的不孕症原因之一。LUFS的病因至今尚不清楚,用传统检查方法如基础体温测定(BBT)、血清孕酮(P)水平测定、子宫内膜活检及宫颈粘液结晶检查等均难以将LUFS周期与正常排卵周期相区分。我院生殖内分泌与不孕门诊,在对不孕患者进行药物诱导排卵和B超监测排卵的过程中发现LUFS两例。其中1例连续2周期出现LUFS。本文对LUFS的发病机理、诊断方法及指标进行了讨论,并就本病提出了一些值得探讨的问题。
Not rupture follicular luteinizing syndrome (LUFS) occurred in women with menstrual disorders and infertility, especially one of the reasons difficult to explain the cause of infertility. The etiology of LUFS remains unclear, and it is difficult to distinguish the LUFS cycle from the normal ovulation cycle using conventional tests such as basal body temperature (BBT), serum progesterone (P) levels, endometrial biopsies, and cervical mucinous crystallography . Reproductive endocrine and infertility clinics in our hospital, infertility patients in the drug-induced ovulation and B-monitoring ovulation process found two cases of LUFS. One case showed LUFS for two consecutive cycles. This article discusses the pathogenesis of LUFS, diagnostic methods and indicators were discussed, and put forward some issues worth exploring.