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目的:探讨视黄醇结合蛋白4(RBP4)超敏C反应蛋白(hsCRP)与糖尿病肺功能变化的关系。方法:选取进入我院治疗的Ⅱ型糖尿病患者(T2DM)50例,对FPG、FINS、RBP4、超敏C反应蛋白、hsCRP测定。并统计FVC、TLC、1s(FEV1)70%-80%、(V25、V50、V75)、DLCO。结果:对照组与糖尿病组肺功能比较有意义,多元线性回归良好。结论:血清RBP4、hsCRP与糖尿病肺功能的发生发展有一定联系,是肺功能的危险因素。
Objective: To investigate the relationship between RBP4 high sensitivity C-reactive protein (hsCRP) and the changes of pulmonary function in diabetic patients. Methods: Fifty patients with type 2 diabetes mellitus (T2DM) admitted to our hospital were enrolled in this study. FPG, FINS, RBP4, hsCRP and hsCRP were measured. FVC, TLC, 1s (FEV1) 70% -80%, (V25, V50, V75) and DLCO were calculated. Results: The lung function in the control group and diabetic group was more significant and the multiple linear regression was good. Conclusion: Serum RBP4 and hsCRP are associated with the occurrence and development of pulmonary function in diabetic patients and are the risk factors of pulmonary function.