论文部分内容阅读
高脂血症是指血浆中一种或多种脂质成分的增高或减低,脂蛋白量和(或)质的改变等。其主要表现为高胆固醇血症、高甘油三酯血症、高密度脂蛋白水平下降或脂蛋白代谢紊乱,可直接引起动脉粥样硬化、冠心病、脑血管病、胰腺炎等。目前他汀类药物是调血脂药物中发展最快同时也是临床使用最多的药物[1]。该类药作用机制通过抑制三羟基三
Hyperlipidemia refers to the increase or decrease of one or more lipid components in the plasma, changes in the amount and / or mass of lipoproteins, and the like. Its main manifestations of hypercholesterolemia, hypertriglyceridemia, high-density lipoprotein levels or lipoprotein metabolism disorders, can directly cause atherosclerosis, coronary heart disease, cerebrovascular disease, pancreatitis and so on. Currently statins are the fastest-growing and also the most clinically used drugs for lipid-lowering drugs [1]. The mechanism of action of such drugs by inhibiting trihydroxy three