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目的探讨带状疱疹患者应用局部注射药物联合放血拔罐治疗的临床疗效。方法 86例带状疱疹患者随机分为观察组和对照组各43例,对照组给予泛昔洛韦片0.25g/次,3次/d,口服;观察组在对照组治疗基础上给予放血、拔罐治疗,并于拔罐后立即局部注射药物(维生素B12 mL+维生素B121 mL+盐酸利多卡因10 mL+地塞米松1 mL),1次/d。2组疗程均为7d。治疗7d后评定临床疗效,记录2组水疱停止产生时间、疼痛缓解时间、皮损完全结痂时间、皮损痊愈时间及不良反应发生情况。结果观察组治疗有效率(95.35%)高于对照组(76.74%)(P<0.05),水疱停止产生时间[(2.06±0.36)d]、疼痛缓解时间[(4.96±1.57)d]、完全结痂时间[(5.79±1.09)d]和皮损痊愈时间[(8.35±3.45)d]较对照组[(4.38±1.34)、(6.85±1.82)、(6.69±1.09)、(10.56±4.10)d]短(P<0.05);2组均未见严重不良反应,观察组不良发应发生率(6.98%)与对照组(9.30%)比较差异无统计学意义(P>0.05)。结论局部药物注射联合放血拔罐治疗带状疱疹疗效满意,不良反应轻。
Objective To investigate the clinical efficacy of topical injection combined with bloodletting and cupping therapy in patients with shingles. Methods Eighty-six patients with herpes zoster were randomly divided into observation group (43 cases) and control group (n = 43). The control group was treated with 0.25g / second famciclovir tablet once daily for 3 times. The observation group was given bloodletting and cupping therapy on the basis of the control group, Immediately after cupping and local injection of drugs (vitamin B12 mL + vitamin B121 + lidocaine hydrochloride 10 mL + dexamethasone 1 mL), 1 time / d. 2 groups of treatment are 7d. After 7 days of treatment, the clinical curative effect was assessed. The time of stopping the production of the blisters, the pain relief time, the time of complete scabbing, the healing time of the skin lesions and the adverse reactions were recorded. Results The effective rate (95.35%) in the observation group was significantly higher than that in the control group (76.74%) (P <0.05), and the time to stop blistering was (2.06 ± 0.36) days and the time to pain relief was (4.96 ± 1.57) days The time of scab [(5.79 ± 1.09) d] and the healing time of skin lesions (8.35 ± 3.45 d) were significantly higher than those of the control group (4.38 ± 1.34, 6.85 ± 1.82, 6.69 ± 1.09, 10.56 ± 4.10, ) d] (P <0.05). No adverse reactions were observed in both groups. There was no significant difference between the two groups (6.98%) and control group (9.30%) (P> 0.05). Conclusion Local drug injection combined with bloodletting cupping treatment of herpes zoster with satisfactory results, mild adverse reactions.