论文部分内容阅读
目的探讨急性ST段抬高性心肌梗死患者采取急诊冠状动脉支架术联合国产替罗非班治疗的效果及安全性。方法将我院2013年1月-2016年6月接诊的急性ST段抬高性心肌梗死患者40例作为研究对象,入选对象临床资料完整,愿意配合本研究,随机分组,每组20例。对照组采取急诊冠状动脉支架术治疗,研究组则加用国产替罗非班治疗,对两组患者临床效果、术后并发症发生率、住院时间,以及术后1个月MACE发生率与LVEF进行观察记录,并对比分析。结果研究组患者支架术成功率稍高于对照组,但比较无差异(P>0.05);两组患者均有出血、血小板减少发生,研究组发生率显著低于对照组(P<0.05);研究组住院时间显著短于对照组(P<0.05);研究组术后1个月MACE发生率显著低于对照组,而LVEF则明显高于对照组(P<0.05)。结论急诊冠状动脉支架术联合国产替罗非班治疗急性ST段抬高性心肌梗死患者,手术成功率高,而且并发症少,术后不良事件少,能更好地改善心功能,值得借鉴。
Objective To investigate the efficacy and safety of emergency T-PCI in patients with acute ST-segment elevation myocardial infarction. Methods Forty patients with acute ST-segment elevation myocardial infarction admitted from January 2013 to June 2016 in our hospital were enrolled in this study. The clinical data of the selected subjects were complete. They were willing to cooperate with this study and were randomly divided into two groups of 20 cases each. The control group was treated with emergency coronary stent. The study group was treated with domestic tirofiban. The clinical effects, the incidence of postoperative complications, hospital stay, MACE incidence and LVEF Observation records, and comparative analysis. Results The success rate of stenting in study group was slightly higher than that in control group (P> 0.05). Hemorrhage and thrombocytopenia occurred in both groups. The incidence of study group was significantly lower than that of control group (P <0.05). The hospitalization time was significantly shorter in the study group than in the control group (P <0.05). The incidence of MACE in the study group was significantly lower than that in the control group at one month after surgery, while the LVEF was significantly higher than that in the control group (P <0.05). Conclusion Emergency coronary artery stenting combined with domestic tirofiban in patients with acute ST-elevation myocardial infarction has a high success rate of operation, less complications, fewer adverse events and better cardiac function, which is worth learning from.