本文对１０个有关肝癌危险因素的病例对照研究原始资料进行了综合分析。病例共９２０例，对照共１０８０例。结果表明：南方地区肝癌危险因素是：ＨＢＶ感染、饮用沟塘水、肝癌家族史；北方地区肝癌危险因素是：ＨＢＶ感染、肝癌家族史、个人既往肝炎史、饮酒因素。我国南北方地区肝癌危险因素构成不尽相同。吸烟与ＨＢｓＡｇ阴性的肝癌有关，而与ＨＢｓＡｇ阳性的肝癌无关。 In this paper, a comprehensive analysis of 10 case-control studies on the risk factors of liver cancer was conducted. A total of 920 cases, a total of 1080 cases. The results showed that the risk factors for hepatocellular carcinoma in southern China were: HBV infection, drinking water from ditch ponds, and a family history of hepatocellular carcinoma; the risk factors for hepatocellular carcinoma in northern China were: HBV infection, family history of hepatocellular carcinoma, previous history of hepatitis, and alcohol intake factors. The composition of risk factors for liver cancer in the northern and southern parts of China is not the same. Smoking is associated with HBsAg-negative liver cancer, but not HBsAg-positive liver cancer.