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目的 为改善脑性瘫痪患儿的预后 ,研究围产期脑损伤儿早期诊断脑瘫的方法。方法 在临床神经发育学检查的基础上 ,检测正中神经体感诱发电位。以月龄分组 ,正常儿做对照 ,判断异常指标。结果 临床筛查出的 84例脑瘫高危儿 ,经体感诱发电位检测异常结果的患者共 60例 ( 71 43 % )。远期随访证实 60例中符合脑瘫诊断标准的 5 3例。其余 2 4例正常结果中脑损伤儿只有 2例为轻型脑瘫。真实发病率为 65 48% ,准确性为 89 2 9% ,敏感性为 96 3 6% ,特异性为 75 86%。结论 围产期脑损伤儿体感诱发电位检测对早期诊断脑瘫是一种客观、灵敏、有效的实验室方法。
Objective To improve the prognosis of children with cerebral palsy and to study the method of early diagnosis of cerebral palsy in children with perinatal brain injury. Methods Based on clinical neurodevelopmental examination, median nerve somatosensory evoked potentials were measured. Grouping by age, normal children as a control to determine abnormal indicators. Results A total of 84 patients (71 43%) with high risk of cerebral palsy and abnormal somatosensory evoked potentials were screened out. Long-term follow-up confirmed 60 cases of cerebral palsy in line with the diagnostic criteria of 53 cases. The remaining 24 cases of normal brain injury in children only 2 cases of mild cerebral palsy. The true incidence was 65 48% with an accuracy of 89 2 9%, a sensitivity of 96 3 6% and a specificity of 75 86%. Conclusion The detection of somatosensory evoked potential in perinatal brain injury is an objective, sensitive and effective laboratory method for the early diagnosis of cerebral palsy.