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本文测定了进口及国产共3种胃铋治片的抗酸曲线并求得达峰时间Tmax、达峰时酸度pHmax及抗酸曲线下面积AUC∞等参数.结果表明不同片剂的抗酸效果有显著差异．以进口片为标准参比制剂，按AUC∞比值求得国产两种片剂的相对抗酸等效性F值分别为107.69±11.48和82.49±14.24％．
In this paper, we measured the acid-fast curve of three kinds of gastric bismuth tablets imported and domestic and obtained the peak time Tmax, acidity peak pHmax and the area under the acid-resistant curve AUC∞ and other parameters.The results showed that different tablets antacid effect There are significant differences. Taking imported tablets as standard reference preparations, the relative antacid equivalence F values of domestic two kinds of tablets obtained by AUC ∞ ratio were 107.69 ± 11.48 and 82.49 ± 14.24% respectively.