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目的观察舒血宁注射液辅助治疗脑梗死的临床疗效。方法选取2013年1月—2015年5月延安大学附属医院神经内科收治的脑梗死患者80例,采用随机数字表法分为对照组和观察组,每组40例。对照组患者给予常规治疗,观察组患者在常规治疗基础上给予舒血宁注射液。比较两组患者治疗前及治疗后7、14 d血清超氧化物歧化酶(SOD)水平、美国国立卫生研究院卒中量表(NIHSS)评分及临床疗效。结果时间与方法在血清SOD水平上存在交互作用(P<0.05),时间在血清SOD水平上主效应显著(P<0.05),方法在血清SOD水平上主效应显著(P<0.05);观察组患者治疗后7、14 d血清SOD水平高于对照组(P<0.05)。时间与方法在NIHSS评分上存在交互作用(P<0.05),时间在NIHSS评分上主效应显著(P<0.05),方法在NIHSS评分上主效应显著(P<0.05);观察组患者治疗后7、14 d NIHSS评分低于对照组(P<0.05)。观察组患者临床疗效优于对照组(P<0.05)。结论舒血宁注射液辅助治疗脑梗死的临床疗效良好。
Objective To observe the clinical effect of Shuxuening injection in the treatment of cerebral infarction. Methods From January 2013 to May 2015, 80 patients with cerebral infarction admitted to the Department of Neurology, Yan’an University Affiliated Hospital were divided into control group and observation group with 40 cases in each group. Patients in the control group were given routine treatment. Patients in the observation group were given Shuxuening injection on the basis of routine treatment. The levels of serum superoxide dismutase (SOD), NIH Stroke Scale (NIHSS) score and clinical efficacy before and after treatment were compared between the two groups. (P <0.05). The main effect of time on serum SOD level was significant (P <0.05), and the main effect of serum SOD level was significant (P <0.05). The observation group The level of serum SOD was higher in the patients on the 7th and 14th days after treatment than that in the control group (P <0.05). There was an interaction between time and method in the NIHSS score (P <0.05), the main effect of time on the NIHSS score was significant (P <0.05), and the main effect was significant (P <0.05) on the NIHSS score; , NIHSS score 14 d lower than the control group (P <0.05). The clinical efficacy of the observation group was better than that of the control group (P <0.05). Conclusion Shuxuening injection in the treatment of cerebral infarction with good clinical efficacy.