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目的探讨慢性乙型肝炎纤维化的治疗方法。方法 2003年9月—2009年10月收治慢性乙型肝炎肝纤维化患者66例,采用阿德福韦酯、干扰素、软肝冲剂联合应用,观察肝功能、血清肝纤维化指标。结果治疗后肝功能ALT、AST、TbiL、Aib均较治疗前有明显改善(P<0.05);血清肝纤维化指标HA、Pcn、CIViC、LM、TNFa也均有明显改善(P<0.05)。结论阿德福韦酯联合干扰素、软肝冲剂治疗慢性乙型肝炎、肝纤维化疗效满意。
Objective To investigate the treatment of chronic hepatitis B fibrosis. Methods From September 2003 to October 2009, 66 patients with chronic hepatitis B liver fibrosis were treated with adefovir dipivoxil, interferon and RuanGan granules. The liver function and serum liver fibrosis indexes were observed. Results After treatment, the ALT, AST, TbiL and Aib of liver function were significantly improved (P <0.05), and the indexes of serum hepatic fibrosis HA, Pcn, CIViC, LM and TNFa also improved obviously. Conclusions Adefovir dipivoxil combined with interferon and Ruangan granules in the treatment of chronic hepatitis B, liver fibrosis with satisfactory results.