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目的:探讨早期先兆流产对围产结局的影响。方法:回顾性分析980例先兆流产患者(研究组)的围产结局,同时选择同期分娩的980例正常妊娠的孕妇为对照组,比较两组产妇子痫前期、胎盘早剥、前置胎盘、胎膜早破、产后出血、手取胎盘发生率以及两组产妇的新生儿早产、死胎、新生儿死亡、小于胎龄儿、Apgar 5 min评分<7分及转入NICU的发生率。结果:早期先兆流产患者的前置胎盘、产后出血、手取胎盘发生率高于对照组的产妇,差异有统计学意义(P<0.05);早期先兆流产患者的子痫前期、胎盘早剥及胎膜早破的发生率与对照组比较差异无统计学意义(P>0.05);早期先兆流产患者的早产、新生儿死亡、小于胎龄儿及转入NICU率高于对照组的产妇,差异有统计学意义(P<0.05);早期先兆流产患者的死胎、Apgar5 min评分<7分的发生率与对照组比较差异无统计学意义(P>0.05)。结论:早期先兆流产会增加不良围产结局,应提高对早期先兆流产患者的产前监护。
Objective: To investigate the impact of early threatened abortion on perinatal outcome. Methods: The perinatal outcome of 980 cases of threatened abortion (study group) was retrospectively analyzed. 980 pregnant women of the same period of delivery were selected as the control group. The preterm preeclampsia, placental abruption, placenta previa, Premature rupture of membranes, postpartum hemorrhage, the incidence of placenta accreta and preterm birth, stillbirth, neonatal death, infants less than gestational age, Apgar 5 min score <7 and incidence of NICU. Results: The incidence of placenta previa, postpartum hemorrhage and placenta accreta in early threatened abortion patients were significantly higher than those in the control group (P <0.05); preeclampsia, placental abruption and fetal The incidence of premature rupture of membranes was not significantly different from that of the control group (P> 0.05). The differences of preterm birth, neonatal death, infants born less than gestational age and NICU transferred into the early threatened abortion were higher than those in the control group Statistical significance (P <0.05). The incidence of stillbirth and Apgar5 min score <7 in early threatened abortion patients was not significantly different from that in control group (P> 0.05). CONCLUSIONS: Early threatened abortion increases adverse perinatal outcomes and should increase prenatal care for patients with early threatened abortion.