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免疫细胞大致可分为髓系细胞和淋系细胞,淋系细胞也就是淋巴细胞。淋巴细胞又可分为特异性淋巴细胞和固有淋巴细胞。近几年来,针对固有淋巴细胞的研究进展迅速。固有淋巴细胞(ILC)是一群来源于共同淋巴祖细胞(CLP),具有固有类细胞特征的淋巴细胞。根据细胞的表型特征、功能差异可以将ILC分为3组。本文将从ILC表型、细胞分化和对疾病的影响等多方面对ILC进行综述。
Immune cells can be roughly divided into myeloid cells and lymphoid cells, lymphoid cells that lymphocytes. Lymphocytes can be divided into specific lymphocytes and innate lymphocytes. In recent years, research on innate lymphocytes has progressed rapidly. Inherent lymphocytes (ILCs) are a group of lymphocytes derived from common lymphoid progenitor cells (CLPs) that are inherently cell-like. According to the phenotypic characteristics of cells, functional differences can be divided into three groups ILC. This article reviews ILCs in terms of ILC phenotypes, cell differentiation and their impact on disease.