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目的:为了建立普服碘盐后新的甲状腺摄131碘率的正常实验室比值。方法:测定70名正常人及224例甲状腺疾病患者的摄131碘率。受检者均空腹口服131碘74~185kbq,用HFa63A型甲状腺功能仪测定3h、24h摄131碘率。结果:普服碘盐后,正常组摄131碘率较80年代明显降低,有非常显著差异(P<0.001),148例甲状腺机能亢进患者的摄131碘率与80年代甲亢患者比无明显差异(P>0.05),其中97例未经治疗的申亢患者与51例经药物治疗的甲亢患者的摄131碘率有非常显著差异(P<0.001)。初诊亚急性甲状腺炎、甲状腺癌患者摄131碘率比正常组明显降低(P<0.001);甲状腺瘤及囊肿、结节性甲状腺肿患者摄131碘率与正常人比无明显差异(P>0.05)。结论:在目前普食碘盐的条件下,我室甲状腺摄131碘率的实验室参比值以3h时>18%、24h时>33%为宜。此外,在做甲状腺摄131碘率时可以不必过多考虑食物中碘的影响因素。
OBJECTIVE: To establish a normal laboratory ratio of new iodine 131 thyroid uptake following generalized iodized salt. Methods: To determine the 131 iodine rate in 70 normal subjects and 224 thyroid disease patients. Subjects were fasting oral 131I 74 ~ 185kbq, with HFa63A thyroid function measured 3h, 24h photo 131 iodine. Results: After iodized salt of general anesthesia, the 131 iodine rate in normal group was significantly lower than that in 80 years (P <0.001), and the ratio of 131 iodine in 148 cases of hyperthyroidism to that of hyperthyroidism in 80’s (P> 0.05). There was a significant difference (P <0.001) in 131 iodine rate among 97 untreated patients with hyperthyroidism and 51 patients with hyperthyroidism treated with drugs. In the newly diagnosed subacute thyroiditis and 131 thyroid cancer patients, the iodine intake rate was significantly lower than that in the normal group (P <0.001). There was no significant difference between the thyroid tumor and the cyst and the nodular goiter patients (P > 0.05). Conclusion: Under the current general condition of iodized salt, the laboratory reference value of iodine uptake rate of 131 thyroid in our department is> 18% at 3h,> 33% at 24h. In addition, the thyroid 131 iodine rate do not have to think too much about the impact of iodine in food.