血管内皮生长因子（ｖａｓｃｕｌａｒ ｅｎｄｏｔｈｅｌｉａｌ ｇｒｏｗｔｈ ｆａｃｔｏｒ，ＶＥＧＦ）是一类新型的多肽生长因子，能促进血管内皮细胞的增殖和新生血管的形成。我们已经报道，采用基因缝线法肌内转移ＶＥＧＦ基因，治疗肢体动脉闭塞症的大鼠和家犬，具有显著疗 Vascular endothelial growth factor (VEGF) is a new type of polypeptide growth factor, which can promote the proliferation of vascular endothelial cells and the formation of neovascularization. We have reported that the use of gene suture intramuscular transfer of VEGF gene in the treatment of limb arterial occlusive disease in rats and dogs, with significant treatment