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作者报告2例急性淋巴细胞性白血病(简称急淋)患儿分别于停止治疗2个月和4个月后,发现白血病细胞浸润眼前房为复发的唯一体征。病例介绍主诉例1左眼,例2右眼,眼红痛、畏光,检查发现患侧瞳孔固定、不规则,虹膜弥漫性增厚,眼前房少量积脓。经穿刺和虹膜活检确诊为白血病细胞浸润眼前房。患眼前房用放射治疗,结合鞘内注射氨甲喋呤(MTX)和全身化疗,治疗后患眼恢复正常。讨论髓外白血病是急淋的重要并发症。白血病细胞侵犯眼前房则罕见,且通常发生在中枢神经系统(CNS)白血病的同时。作者复习文献,在化疗结束
The authors report 2 children with acute lymphoblastic leukemia (acute lymphoblastic) were stopped treatment for 2 months and 4 months respectively, found that leukemia cells infiltrating the anterior chamber of the eye is the only sign of recurrence. Case description Main case 1 left eye, 2 cases of right eye, eye red pain, photophobia, examination found ipsilateral pupil fixed, irregular, iris diffuse thickening, anterior chamber a small amount of empyema. After puncture and iris biopsy confirmed leukemia cells infiltrating the anterior chamber. Pre-existing room radiation therapy, combined with intrathecal methotrexate (MTX) and systemic chemotherapy, the affected eyes returned to normal after treatment. Discussion Extramedullary leukemia is an important complication of acute leaching. Leukemia cells that invade the anterior chamber are rare and usually occur at the same time as central nervous system (CNS) leukemia. The authors review the literature at the end of chemotherapy