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目的:探讨单磷酸阿糖腺苷(Ara-adeno.sin.e)治疗小儿手足口病(HFMD)的临床疗效。方法:选择1~6岁患手足口病患儿80例随机分为2组,治疗组给予单磷酸阿糖腺苷,对照组给予利巴韦林治疗,对临床症状和体征的变化进行分析。结果:治疗组临床症状和体征均较对照组消失早(P<0.01)。结论:单磷酸阿糖腺苷治疗小儿手足口病疗程短,见效快,有明显疗效。
Objective: To investigate the clinical efficacy of Ara-adeno.sin.e in the treatment of HFMD in children. Methods: Eighty children with hand-foot-mouth disease aged 1 to 6 were randomly divided into two groups. The treatment group was given adenosine monophosphate. The control group was treated with ribavirin, and the changes of clinical symptoms and signs were analyzed. Results: The clinical symptoms and signs disappeared in the treatment group as compared with the control group (P <0.01). Conclusion: Ara-A monophosphate treatment of children with hand-foot-mouth disease short course of treatment, quick, significant effect.