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目的 探讨低容量经尿道前列腺电切术 (low volumeTURP)治疗良性前列腺增生的临床效果及安全性。 方法 对 76例高危良性前列腺增生患者采用标准TURP(39例 )和低容量TURP(37例 )手术治疗。对 2组手术时间、术中出血量、术后膀胱冲洗时间、手术并发症、术后IPSS、最大尿流率(Qmax)、剩余尿量变化值等进行比较。 结果 标准TURP组和低容量TURP组平均手术时间分别为(6 7.5± 18.2 )、(16 .4± 3.5 )min(P =0 .0 11) ;术中出血量分别为 (15 8.4± 4 7.3)、(5 4 .7± 2 5 .2 )ml(P =0 .0 13) ;术后膀胱冲洗时间分别为 (4 .9± 1.8)、(1.3± 0 .5 )d(P =0 .0 2 9) ;术后住院时间分别为 (7.6± 2 .9)、(2 .4± 1.3)d(P =0 .0 37)。IPSS评分分别降低 19.3± 7.6、15 .3± 9.7(P =0 .4 6 ) ;剩余尿量分别减少(134.9± 6 8.6 )、(16 3.8± 94 .5 )ml(P =0 .17) ;最大尿流率分别增加 (13.4± 8.8)、(11.7± 9.1)ml/s(P =0 .79)。 37例低容量TURP病例中 31例随访 2～ 18个月 ,平均 10个月 ,疗效满意。 结论 低容量TURP治疗BPH有效 ,具有手术时间短、创伤小等优点 ,增加了高危患者对手术的耐受性。
Objective To investigate the clinical effect and safety of low volume transurethral resection of prostate (TURP) in the treatment of benign prostatic hyperplasia. Methods Totally 76 high-risk patients with benign prostatic hyperplasia were treated with standard TURP (39 cases) and low-capacity TURP (37 cases). The operation time, intraoperative blood loss, postoperative bladder irrigation time, surgical complications, postoperative IPSS, maximum flow rate (Qmax) and residual urine volume changes were compared. Results The average operation time of the standard TURP group and the low-volume TURP group was (6 7.5 ± 18.2) and (16.4 ± 3.5) min (P 0. 01) respectively. The intraoperative blood loss was (15 8.4 ± 4 7.3 ), (54.7 ± 25.2) ml (P = 0.013), respectively. The postoperative bladder washing time were (4.9 ± 1.8), (1.3 ± 0.5, .0 2 9). The postoperative hospital stay was (7.6 ± 2.9) days and (2.4 ± 1.3) days (P = 0.037). The IPSS scores decreased by 19.3 ± 7.6 and 15.3 ± 9.7, respectively (P = 0.46), while the residual urine volume decreased by 134.9 ± 6 8.6 and 16 3.8 ± 94.5 respectively (P = 0.17) ; The maximal uroflow rate increased by (13.4 ± 8.8) and (11.7 ± 9.1) ml / s, respectively (P = 0.79). Thirty-seven cases of low-volume TURP cases were followed up for 2 to 18 months, with an average of 10 months, with satisfactory results. Conclusion Low-volume TURP is effective in treating BPH. It has the advantages of short operation time and small trauma, and increases the tolerance to surgery in high-risk patients.