在临床上冠心病的无创性诊断方法有多种,就负荷心肌灌注显像而言,包括了运动负荷和药物负荷,本文对各方面资料的综合分析后认为腺苷通过其多方面的作用机制引起冠脉的扩张,是其核素心肌显像的基础,并且由于其副作用少,作用时间短,诊断敏感性和特异性均较高而在临床上被认为是诊断冠心病的最可靠的无创性方法,但就腺苷与不同的心肌显像剂结合(99mTcsestimib和99mTcTetrofosmin)是否能更好的提高诊断率有待论证。 Clinically, there are many noninvasive diagnostic methods for coronary heart disease. In terms of myocardial perfusion imaging, including exercise load and drug load, we conclude that adenosine, through its multifaceted mechanism of action, Cause the expansion of coronary artery is the basis of its radionuclide myocardial imaging, and because of its less side effects, short duration of action, the diagnosis of high sensitivity and specificity in the clinical diagnosis of coronary heart disease is considered the most reliable non-invasive However, it remains to be seen whether adenosine binding to different myocardial imaging agents (99mTcsestimib and 99mTcTetrofosmin) can improve the diagnosis rate.