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目的探析急性下肢深静脉血栓临床有效治疗方法及效果。方法选择2015年5月—2017年5月该院收治的急性下肢深静脉血栓患者60例,依据随机原则将全部患者平均分成对照组30例,单独应用低分子肝素治疗,观察组30例,接受替罗非班、低分子肝素联合治疗,比较两组临床疗效。结果观察组治疗2周后膝上15 cm、膝下10 cm下肢肢围差分别为(2.41±0.37)、(1.45±0.42)cm,静脉闭塞程度为(50.13±1.66)%,对照组分别为(3.95±0.41)cm、(2.56±0.45)cm、(70.35±1.32)%;治疗2周后两组PT、APTT、TT指标差异无统计学意义,观察组FIB指标明显高于对照组。结论替罗非班、低分子肝素联合治疗急性下肢深静脉血栓能够帮助患者肿胀以及静脉闭塞情况得到改善,同时不会影响凝血功能,值得广泛应用。
Objective To explore the clinical effective treatment of acute lower extremity deep vein thrombosis and its effects. Methods From May 2015 to May 2017, 60 patients with acute DVT in our hospital were randomly divided into control group (30 cases) Tirofiban, low molecular weight heparin combined treatment, the clinical efficacy of two groups were compared. Results After 2 weeks of treatment, the limb circumference of the knee in 15 cm of knee and 10 cm of knee in the observation group were (2.41 ± 0.37) and (1.45 ± 0.42) cm respectively, the degree of venous occlusion was (50.13 ± 1.66)% in the observation group and 3.95 ± 0.41 cm, (2.56 ± 0.45) cm, (70.35 ± 1.32)% respectively. There was no significant difference in PT, APTT and TT indexes between the two groups after 2 weeks of treatment. The FIB index in the observation group was significantly higher than that in the control group. Conclusion The combination of tirofiban and LMWH in the treatment of acute deep venous thrombosis of lower extremity can help to improve the patients’ swelling and venous occlusion, and will not affect the coagulation function. Therefore, it is worth to be widely used.