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过去的研究表明,肿瘤深度和瘤细胞倍体与肿瘤的生物学行为有关,但这些参数与颈部复发的关系如何却不清楚,亦未应用到普遍接受的分期系统中。肿瘤血管生成是近年来一个比较活跃的研究领域。已经发现,肿瘤血管生成与乳腺癌、结肠癌和口腔肿瘤的侵袭性相关,但Leedy等在舌癌研究中却未证实这一结果。作者对25例舌癌患者进行回顾研究,旨在评价肿瘤血管生成与Ⅰ期舌癌的关系。
Previous studies have shown that tumor depth and tumor cell ploidy and tumor biological behavior, but these parameters and neck recurrence of the relationship is not clear, nor applied to the commonly accepted staging system. Tumor angiogenesis is a relatively active research field in recent years. It has been found that tumor angiogenesis is associated with invasiveness of breast, colon and oral tumors, but Leedy et al. Did not confirm this result in tongue cancer studies. The authors conducted a retrospective study of 25 patients with tongue cancer to evaluate the relationship between tumor angiogenesis and stage I tongue cancer.