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方法 研究共入选来自4个不同地区的医学中心422例患者,年龄>21岁,入选前连续≥7天服用阿司匹林,排除标准包括:(1)入选前1周服用过糖蛋白Ⅱb/Ⅲa拮抗剂、噻氯匹定(ticlopidine)、双嘧达莫(dipyridamole)、氯吡格雷(clopidogrel)、非三环氧化酶-2-特异性的非甾体类消炎药和任何甾体类药物;(2)曾发生或有类似家族史:出血或血栓性疾病、血小板计数<100000/μl或>450000/μl、严重贫血(Hb<8g/dl);(3)入选前1周有较大手术史。血样采集后放置在含3.2％枸橼酸钠真
METHODS: A total of 422 patients from a medical center in 4 different regions aged> 21 years were enrolled in this study. Aspirin was administered for ≥7 consecutive days before inclusion. Exclusion criteria included: (1) administration of glycoprotein IIb / IIIa antagonist Ticlopidine, dipyridamole, clopidogrel, non-tricyclic oxidase-2-specific non-steroidal anti-inflammatory drugs and any steroidal drugs; (2 ) Had or had a similar family history of bleeding or thrombotic disease, platelet count <100000 / μl or> 450000 / μl, severe anemia (Hb <8g / dl); Blood samples collected after containing 3.2% sodium citrate true