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骨和软组织肉瘤的治疗,常采用根治性的外科切除术,包括截肢。但对一些病例,特别是低分化肉瘤.术后复发率也可达10～25％。 Morton和Eilber首先提出了一种术前治疗的方法,即动脉内局部化疗加快速分割的放疗。对Ⅲ期肉瘤或已有局部复发的患者,治疗也获得了成功。 本文对30名骨和软组织肉瘤的患者,进行此法治疗.患者都是Ⅲ期的低分化肉瘤或靠近大血管、骨骼和神经的大肉瘤,按常规需要截肢的;还包括有局部复发和有局限性肺转移适合切除者。
The treatment of bone and soft tissue sarcomas often uses radical surgical resection, including amputation. However, in some cases, especially poorly differentiated sarcoma, the recurrence rate can reach 10-25%. Morton and Eilber first proposed a preoperative treatment method, namely intra-arterial local chemotherapy plus fast-separation radiotherapy. Treatment has also been successful in patients with stage III sarcoma or those who have had local recurrence. In this article, 30 patients with bone and soft tissue sarcoma were treated with this method. All patients were stage III poorly differentiated sarcomas or large sarcomas close to large blood vessels, bones, and nerves, which were routinely amputated; they also included local recurrence and Localized lung metastases are suitable for resection.