中药蔓荆子味辛苦,性微寒,具疏散风热,清利头目功效,中医常用于偏正头痛,目赤肿痛等症。有关其炮制历史,早在南北朝《雷公炮炙沦》中就有“用酒浸一伏时后蒸”的记载.目前蔓荊子的炮制,多采用炒黄法(中国药典)、酒炒法(厦门)、蒸法(广东),少数地区还有炒焦法、蜜炙法(西安、南京、长沙、重庆)等。关于蔓荊子炮制的现代研究目前未见报道。为此,本文测定了蔓荆子生品、炒黄品、炒焦品的水煎出物、醇浸出物含量,并比较了生品与炒黄制品对小白鼠的镇痛作用。试图对其炮制作用作出初步评价。 Chinese medicine Vitex is very hard, slightly cold, with evacuation of wind and heat, Qingli boss effect, Chinese medicine is often used to correct a headache, red eyes and throat embolism. Regarding its history of concocting, as early as in the Northern and Southern Dynasties, “the Leigong Artillery,” there is “use wine immersed in a volt, then steamed” records. At present, Vitex cultivation, more use of fried yellow method (Chinese Pharmacopoeia), wine fried method (Xiamen), steaming method (Guangdong), Chaochao method, candied fruit method (Xi’an, Nanjing, Changsha, Chongqing) are also available in a few areas. Modern research on the preparation of Vitex negundo has not been reported at present. For this reason, the contents of water extracts and alcohol extracts of Vitex negundo seeds, fried yellow products, and fried coke products were determined in this paper, and the analgesic effects of raw products and fried yellow products on mice were compared. Try to make a preliminary assessment of its artillery production.