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目的通过临床观察,探讨局部进展期中低位直肠癌术前辅助放化疗后手术间隔期差异对患者肛门功能的影响。方法选择2010年3月~2013年5月进入本院进行直肠癌手术治疗的患者150例,将患者分为①单纯放疗组(A组75例),并在此基础上给予常规手术治疗;②同期放疗组(B组75例),在给予希罗达+同期放疗后再予以手术,对两组患者保肛率进行比较分析。结果治疗结束随访的第3个月发现,A组患者共10例出现不同程度的肛门失禁;B组患者共出现6例不同程度的肛门失禁,两组患者手术前后肛肠压力比较结果显示显著,B组优势明显,P<0.05。结论同期放疗效果显著,可减少患者肛门功能失禁率,是术后的保肛效果得到有效的执行,提高了患者生活质量。
Objective To investigate the effect of preoperative adjuvant chemotherapy and radiotherapy on anal function in patients with locally advanced low-grade rectal cancer after surgery. Methods 150 patients admitted to our hospital from March 2010 to May 2013 were enrolled in this study. The patients were divided into ① radiotherapy group (75 cases in group A), and on the basis of conventional surgical treatment; ② The same period radiotherapy group (group B, 75 cases), given Xeloda + concurrent radiotherapy and then surgery, the two groups of patients anal ratio were analyzed. Results In the third month after the end of treatment, there were 10 cases of anal incontinence in group A, 6 cases of anal incontinence in group B, and the anorectal pressure before and after operation showed significant difference between the two groups Group has obvious advantages, P <0.05. Conclusions The radiotherapy has a significant effect in the same period, which can reduce the anus incontinence rate in patients. It is an effective anal-retention effect after operation, and improves the quality of life of patients.