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经研究发现亚急粒细胞白血病细胞形态较为特殊。各种组化染色阳性物质呈团块状且位于核的凹陷处；电镜下易发现特殊的包含体。临床病程较Ｍ＿２ａ长，发病缓渐，易发生神经系统等髓外浸润。核型分析有ｔ（８；２１），常伴有性染色体丢失。免疫表型分析符合为分化较好的粒细胞白血病；有ＡＭＬ＿１－ＥＴＯ融合基因。在我国年发病率为０．１９４／１０￣５。
The study found that the morphology of leukemia leukemia cells is more special. A variety of histochemically stained positive materials were clumpy and located in the depression of the nucleus; special inclusion bodies were easily found under electron microscope. The clinical course is longer than that of M_2a, and the onset is gradual and prone to extramedullary infiltration of the nervous system. There are t(8;21) karyotype analyses, often accompanied by loss of sex chromosomes. The immunophenotype analysis was consistent with well-differentiated granulocytic leukemia; there was an AML 1 -ETO fusion gene. The annual incidence rate in China is 0.194/10 to 5.