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已报导,由于雌激素对脂类代谢的影响,致使服用复方口服避孕药(OC)的妇女心血管疾病发病率增加。为此作者研究了一种所谓分三期口服的OC对血浆脂类、高密度脂蛋白(HDL)和血浆性激素结合球蛋白(SHBG)的影响,并与三种常规配伍的OC进行了比较。认为适当配伍的OC可使脂蛋白的变化最小。作者选择了98名无血栓病史、肝脏病史,月经正常的妇女做受试者,她们在受试前6个月内没有
It has been reported that the incidence of cardiovascular disease in women taking Compound Oral Contraceptives (OC) is increased due to the effect of estrogen on lipid metabolism. To do this, we investigated the effects of a so-called three-phase orally administered OC on plasma lipids, high density lipoprotein (HDL), and plasma sex hormone-binding globulin (SHBG) and compared them to three conventional compatible OCs. OC considered appropriate compatibility of lipoprotein can make the smallest changes. The authors selected 98 women with no history of thrombosis, a history of liver disease, and normal menstruation as subjects who did not have their disease within 6 months before the test