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目的:探讨血液灌流与血液透析滤过联合抢救重度有机磷农药中毒的临床效果。方法:选择怀集县人民医院2011年1月-2014年1月之间收治的100例急性重度有机磷农药中毒患者为观察对象,随机将其分为对照组和观察组,每组50例。对照组接受血液透析治疗,观察组接受血液灌流与血液透析滤过联合治疗,回顾分析两组患者疗效。结果:观察组在住院时间、中间综合征、阿托品用量等观察指标以及总有效率等方面均明显优于对照组,差异有统计学意义(P<0.05)。结论:血液灌流联合血液透析滤过治疗急性重度有机磷中毒具有较为理想的临床效果。
Objective: To investigate the clinical effect of hemoperfusion combined with hemodiafiltration in the treatment of severe organophosphorus pesticide poisoning. Methods: One hundred patients with acute severe organophosphorus pesticide poisoning who were treated in Huaiji County People’s Hospital from January 2011 to January 2014 were selected as observation subjects and randomly divided into control group and observation group, 50 cases in each group. The control group received hemodialysis treatment. The observation group received combination of hemoperfusion and hemodiafiltration, and the curative effect of the two groups was retrospectively analyzed. Results: The observation group was significantly better than the control group in the observation group such as length of hospital stay, intermediate syndrome, atropine dosage and the total effective rate, the difference was statistically significant (P <0.05). Conclusion: Hemoperfusion combined with hemodiafiltration in the treatment of acute severe organophosphate poisoning has an ideal clinical effect.