B淋巴细胞通过形成抗原特异性免疫球蛋白在免疫过程中具有重要的作用。哺乳类动物B细胞分化最早部位是在胚胎早期的卵黄囊, 随后发生于胎肝, 在个体出生后进一步在骨髓中发育, 在外周淋巴器官中成熟。成熟B细胞定居于周围淋巴组织, 如淋巴结皮质浅层和脾的红髓及白髓的淋巴 B lymphocytes play an important role in the immune process by forming antigen-specific immunoglobulins. The earliest site of mammalian B cell differentiation is in the early yolk sac of the embryo, which occurs later in the fetal liver, develops further in the bone marrow after birth, and matures in peripheral lymphoid organs. Mature B cells colonize peripheral lymphatic tissues, such as the lymph node cortex superficial and spleen red pulp and white pulp lymph